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The Importance of Alpha-Actinin Proteins in Platelet Formation and Function, and Their Causative Role in Congenital Macrothrombocytopenia

The actin cytoskeleton plays a central role in platelet formation and function. Alpha-actinins (actinins) are actin filament crosslinking proteins that are prominently expressed in platelets and have been studied in relation to their role in platelet activation since the 1970s. However, within the p...

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Detalles Bibliográficos
Autores principales: O’Sullivan, Leanne R., Cahill, Mary R., Young, Paul W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431150/
https://www.ncbi.nlm.nih.gov/pubmed/34502272
http://dx.doi.org/10.3390/ijms22179363