Rutaecarpine Increases Nitric Oxide Synthesis via eNOS Phosphorylation by TRPV1-Dependent CaMKII and CaMKKβ/AMPK Signaling Pathway in Human Endothelial Cells

Rutaecarpine (RUT) is a bioactive alkaloid isolated from the fruit of Evodia rutaecarpa that exerts a cellular protective effect. However, its protective effects on endothelial cells and its mechanism of action are still unclear. In this study, we demonstrated the effects of RUT on nitric oxide (NO)...

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Detalles Bibliográficos
Autores principales: Lee, Gi Ho, Kim, Chae Yeon, Zheng, Chuanfeng, Jin, Sun Woo, Kim, Ji Yeon, Lee, Seung Yeon, Kim, Mi Yeon, Han, Eun Hee, Hwang, Yong Pil, Jeong, Hye Gwang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431268/
https://www.ncbi.nlm.nih.gov/pubmed/34502308
http://dx.doi.org/10.3390/ijms22179407

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431268/
https://www.ncbi.nlm.nih.gov/pubmed/34502308
http://dx.doi.org/10.3390/ijms22179407

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