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Rutaecarpine Increases Nitric Oxide Synthesis via eNOS Phosphorylation by TRPV1-Dependent CaMKII and CaMKKβ/AMPK Signaling Pathway in Human Endothelial Cells
Rutaecarpine (RUT) is a bioactive alkaloid isolated from the fruit of Evodia rutaecarpa that exerts a cellular protective effect. However, its protective effects on endothelial cells and its mechanism of action are still unclear. In this study, we demonstrated the effects of RUT on nitric oxide (NO)...
Autores principales: | Lee, Gi Ho, Kim, Chae Yeon, Zheng, Chuanfeng, Jin, Sun Woo, Kim, Ji Yeon, Lee, Seung Yeon, Kim, Mi Yeon, Han, Eun Hee, Hwang, Yong Pil, Jeong, Hye Gwang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431268/ https://www.ncbi.nlm.nih.gov/pubmed/34502308 http://dx.doi.org/10.3390/ijms22179407 |
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