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Fc Receptor Variants and Disease: A Crucial Factor to Consider in the Antibody Therapeutics in Clinic

The fragment crystallizable (Fc) domain of antibodies is responsible for their protective function and long-lasting serum half-life via Fc-mediated effector function, transcytosis, and recycling through its interaction with Fc receptors (FcRs) expressed on various immune leukocytes, epithelial, and...

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Detalles Bibliográficos
Autores principales: Kim, Jin, Lee, Ji Young, Kim, Han Gil, Kwak, Min Woo, Kang, Tae Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431278/
https://www.ncbi.nlm.nih.gov/pubmed/34502398
http://dx.doi.org/10.3390/ijms22179489