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Fc Receptor Variants and Disease: A Crucial Factor to Consider in the Antibody Therapeutics in Clinic
The fragment crystallizable (Fc) domain of antibodies is responsible for their protective function and long-lasting serum half-life via Fc-mediated effector function, transcytosis, and recycling through its interaction with Fc receptors (FcRs) expressed on various immune leukocytes, epithelial, and...
Autores principales: | Kim, Jin, Lee, Ji Young, Kim, Han Gil, Kwak, Min Woo, Kang, Tae Hyun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431278/ https://www.ncbi.nlm.nih.gov/pubmed/34502398 http://dx.doi.org/10.3390/ijms22179489 |
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