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Mesenchymal Stem Cell-Conditioned Media Regulate Steroidogenesis and Inhibit Androgen Secretion in a PCOS Cell Model via BMP-2

Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women. Previous studies have demonstrated the therapeutic efficacy of human bone marrow mesenchymal stem cells (BM-hMSCs) for PCOS; however, the regulatory mechanism remains unknown. Bone morphogenetic proteins (BMPs) secreted...

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Detalles Bibliográficos
Autores principales: Chugh, Rishi Man, Park, Hang-soo, Esfandyari, Sahar, Elsharoud, Amro, Ulin, Mara, Al-Hendy, Ayman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431467/
https://www.ncbi.nlm.nih.gov/pubmed/34502090
http://dx.doi.org/10.3390/ijms22179184