Neoantigen-Specific T-Cell Immune Responses: The Paradigm of NPM1-Mutated Acute Myeloid Leukemia

The C-terminal aminoacidic sequence from NPM1-mutated protein, absent in normal human tissues, may serve as a leukemia-specific antigen and can be considered an ideal target for NPM1-mutated acute myeloid leukemia (AML) immunotherapy. Different in silico instruments and in vitro/ex vivo immunologica...

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Detalles Bibliográficos
Autores principales: Forghieri, Fabio, Riva, Giovanni, Lagreca, Ivana, Barozzi, Patrizia, Bettelli, Francesca, Paolini, Ambra, Nasillo, Vincenzo, Lusenti, Beatrice, Pioli, Valeria, Giusti, Davide, Gilioli, Andrea, Colasante, Corrado, Galassi, Laura, Catellani, Hillary, Donatelli, Francesca, Talami, Annalisa, Maffei, Rossana, Martinelli, Silvia, Potenza, Leonardo, Marasca, Roberto, Tagliafico, Enrico, Manfredini, Rossella, Trenti, Tommaso, Comoli, Patrizia, Luppi, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431540/
https://www.ncbi.nlm.nih.gov/pubmed/34502069
http://dx.doi.org/10.3390/ijms22179159

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