Cargando…

Emerging Role of Chimeric RNAs in Cell Plasticity and Adaptive Evolution of Cancer Cells

SIMPLE SUMMARY: Fusion of exons or introns from two different genes can lead to the formation of chimeric RNAs. Several recent studies have reported that chimeric RNAs promote tumorigenesis and cancer drug resistance. Therefore, chimeric RNAs are crucial for generating phenotypic diversity between c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mukherjee, Sumit, Heng, Henry H., Frenkel-Morgenstern, Milana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431553/ https://www.ncbi.nlm.nih.gov/pubmed/34503137 http://dx.doi.org/10.3390/cancers13174328

Ejemplares similares

The Landscape of Novel Expressed Chimeric RNAs in Rheumatoid Arthritis
por: Detroja, Rajesh, et al.
Publicado: (2022)

The Landscape of Expressed Chimeric Transcripts in the Blood of Severe COVID-19 Infected Patients
por: Mukherjee, Sunanda Biswas, et al.
Publicado: (2023)

mRNA-lncRNA Co-Expression Network Analysis Reveals the Role of lncRNAs in Immune Dysfunction during Severe SARS-CoV-2 Infection
por: Mukherjee, Sumit, et al.
Publicado: (2021)

Computational analysis of sense-antisense chimeric transcripts reveals their potential regulatory features and the landscape of expression in human cells
por: Mukherjee, Sumit, et al.
Publicado: (2021)

Novel domain combinations in proteins encoded by chimeric transcripts
por: Frenkel-Morgenstern, Milana, et al.
Publicado: (2012)

Incipient Sympatric Speciation and Evolution of Soil Bacteria Revealed by Metagenomic and Structured Non-Coding RNAs Analysis
por: Mukherjee, Sumit, et al.
Publicado: (2022)

ChiTaRS 2.1—an improved database of the chimeric transcripts and RNA-seq data with novel sense–antisense chimeric RNA transcripts
por: Frenkel-Morgenstern, Milana, et al.
Publicado: (2014)

Immunoinformatics and Structural Analysis for Identification of Immunodominant Epitopes in SARS-CoV-2 as Potential Vaccine Targets
por: Mukherjee, Sumit, et al.
Publicado: (2020)

ChiPPI: a novel method for mapping chimeric protein–protein interactions uncovers selection principles of protein fusion events in cancer
por: Frenkel-Morgenstern, Milana, et al.
Publicado: (2017)

Design principles of gene evolution for niche adaptation through changes in protein–protein interaction networks
por: Carmi, Gon, et al.
Publicado: (2020)

ChiTaH: a fast and accurate tool for identifying known human chimeric sequences from high-throughput sequencing data
por: Detroja, Rajesh, et al.
Publicado: (2021)

Seasonal UV exposure and vitamin D: association with the dynamics of COVID‐19 transmission in Europe
por: Mukherjee, Sunanda Biswas, et al.
Publicado: (2021)

ChiTaRS-3.1—the enhanced chimeric transcripts and RNA-seq database matched with protein–protein interactions
por: Gorohovski, Alessandro, et al.
Publicado: (2017)

ChiTaRS 5.0: the comprehensive database of chimeric transcripts matched with druggable fusions and 3D chromatin maps
por: Balamurali, Deepak, et al.
Publicado: (2020)

Landscape of Chimeric RNAs in Non-Cancerous Cells
por: Chen, Chen, et al.
Publicado: (2021)

COVID19 Drug Repository: text-mining the literature in search of putative COVID19 therapeutics
por: Tworowski, Dmitry, et al.
Publicado: (2020)

Chimeras taking shape: Potential functions of proteins encoded by chimeric RNA transcripts
por: Frenkel-Morgenstern, Milana, et al.
Publicado: (2012)

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data
por: Frenkel-Morgenstern, Milana, et al.
Publicado: (2013)

Recurrent chimeric fusion RNAs in non-cancer tissues and cells
por: Babiceanu, Mihaela, et al.
Publicado: (2016)

EvoProDom: evolutionary modeling of protein families by assessing translocations of protein domains
por: Carmi, Gon, et al.
Publicado: (2021)

The landscape of chimeric RNAs in non-diseased tissues and cells
por: Singh, Sandeep, et al.
Publicado: (2020)

The Landscape and Implications of Chimeric RNAs in Cervical Cancer
por: Wu, Peng, et al.
Publicado: (2018)

Gene fusions and chimeric RNAs, and their implications in cancer
por: Wu, Hao, et al.
Publicado: (2019)

Adaptive responses and invasion: the role of plasticity and evolution in snail shell morphology
por: Kistner, Erica J, et al.
Publicado: (2013)

Chimeric RNAs Discovered by RNA Sequencing and Their Roles in Cancer and Rare Genetic Diseases
por: Sun, Yunan, et al.
Publicado: (2022)

Evidence for Transcript Networks Composed of Chimeric RNAs in Human Cells
por: Djebali, Sarah, et al.
Publicado: (2012)

Refining intra-protein contact prediction by graph analysis
por: Frenkel-Morgenstern, Milana, et al.
Publicado: (2007)

One-Block CYRCA: an automated procedure for identifying multiple-block alignments from single block queries
por: Frenkel-Morgenstern, Milana, et al.
Publicado: (2005)

Common Peptides Study of Aminoacyl-tRNA Synthetases
por: Gottlieb, Assaf, et al.
Publicado: (2011)

Adaptive Transcriptome Profiling of Subterranean Zokor, Myospalax baileyi, to High- Altitude Stresses in Tibet
por: Cai, Zhenyuan, et al.
Publicado: (2018)

The Evolution of Chimeric Antigen Receptor T-Cell Therapy in Children, Adolescents and Young Adults with Acute Lymphoblastic Leukemia
por: Ragoonanan, Dristhi, et al.
Publicado: (2022)

The emerging role of cancer cell plasticity and cell-cycle quiescence in immune escape
por: Bruschini, Sara, et al.
Publicado: (2020)

Transposable Elements Adaptive Role in Genome Plasticity, Pathogenicity and Evolution in Fungal Phytopathogens
por: Mat Razali, Nurhani, et al.
Publicado: (2019)

Art in Science Competition invites artworks to the annual exhibition on ISMB 2018 in Chicago
por: Welch, Lonnie, et al.
Publicado: (2018)

Art in Science Competition invites artworks to the annual exhibition on ISMB 2018 in Chicago
por: Frenkel-Morgenstern, Milana, et al.
Publicado: (2018)

ProtFus: A Comprehensive Method Characterizing Protein-Protein Interactions of Fusion Proteins
por: Tagore, Somnath, et al.
Publicado: (2019)

Emerging roles of endoplasmic reticulum stress in the cellular plasticity of cancer cells
por: Wang, Hao, et al.
Publicado: (2023)

Genes adopt non-optimal codon usage to generate cell cycle-dependent oscillations in protein levels
por: Frenkel-Morgenstern, Milana, et al.
Publicado: (2012)

Maintenance of Protein Synthesis Reading Frame by EF-P and m(1)G37-tRNA
por: Gamper, Howard B., et al.
Publicado: (2015)

The UGG Isoacceptor of tRNA(Pro) Is Naturally Prone to Frameshifts
por: Gamper, Howard B., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_md5o5e187spgn1q5div7nv5qvf