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S-Adenosylmethionine Increases the Sensitivity of Human Colorectal Cancer Cells to 5-Fluorouracil by Inhibiting P-Glycoprotein Expression and NF-κB Activation

Colorectal cancer (CRC) is the second deadliest cancer worldwide despite significant advances in both diagnosis and therapy. The high incidence of CRC and its poor prognosis, partially attributed to multi-drug resistance and antiapoptotic activity of cancer cells, arouse strong interest in the ident...

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Detalles Bibliográficos
Autores principales: Mosca, Laura, Pagano, Martina, Borzacchiello, Luigi, Mele, Luigi, Russo, Annapina, Russo, Giulia, Cacciapuoti, Giovanna, Porcelli, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431578/
https://www.ncbi.nlm.nih.gov/pubmed/34502219
http://dx.doi.org/10.3390/ijms22179286