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S-Adenosylmethionine Increases the Sensitivity of Human Colorectal Cancer Cells to 5-Fluorouracil by Inhibiting P-Glycoprotein Expression and NF-κB Activation
Colorectal cancer (CRC) is the second deadliest cancer worldwide despite significant advances in both diagnosis and therapy. The high incidence of CRC and its poor prognosis, partially attributed to multi-drug resistance and antiapoptotic activity of cancer cells, arouse strong interest in the ident...
Autores principales: | Mosca, Laura, Pagano, Martina, Borzacchiello, Luigi, Mele, Luigi, Russo, Annapina, Russo, Giulia, Cacciapuoti, Giovanna, Porcelli, Marina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431578/ https://www.ncbi.nlm.nih.gov/pubmed/34502219 http://dx.doi.org/10.3390/ijms22179286 |
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