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The Clinical Utility of Optical Genome Mapping for the Assessment of Genomic Aberrations in Acute Lymphoblastic Leukemia

SIMPLE SUMMARY: The stratification of childhood ALL is currently based on various diagnostic assays. This study investigates the feasibility of Optical Genome Mapping (OGM) to determine the genetic risk profile of ALL using fresh and frozen blood cells in an all-in-one approach. Acute lymphoblastic...

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Detalles Bibliográficos
Autores principales: Lühmann, Jonathan Lukas, Stelter, Marie, Wolter, Marie, Kater, Josephine, Lentes, Jana, Bergmann, Anke Katharina, Schieck, Maximilian, Göhring, Gudrun, Möricke, Anja, Cario, Gunnar, Žaliová, Markéta, Schrappe, Martin, Schlegelberger, Brigitte, Stanulla, Martin, Steinemann, Doris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431583/
https://www.ncbi.nlm.nih.gov/pubmed/34503197
http://dx.doi.org/10.3390/cancers13174388