Complement Factor B Mediates Ocular Angiogenesis through Regulating the VEGF Signaling Pathway

Complement factor B (CFB), a 95-kDa protein, is a crucial catalytic element of the alternative pathway (AP) of complement. After binding of CFB to C3b, activation of the AP depends on the proteolytic cleavage of CFB by factor D to generate the C3 convertase (C3bBb). The C3 convertase contains the ca...

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Detalles Bibliográficos
Autores principales: Murray, Hannah, Qiu, Beiying, Ho, Sze Yuan, Wang, Xiaomeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431595/
https://www.ncbi.nlm.nih.gov/pubmed/34502486
http://dx.doi.org/10.3390/ijms22179580

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431595/
https://www.ncbi.nlm.nih.gov/pubmed/34502486
http://dx.doi.org/10.3390/ijms22179580

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