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Complement Factor B Mediates Ocular Angiogenesis through Regulating the VEGF Signaling Pathway
Complement factor B (CFB), a 95-kDa protein, is a crucial catalytic element of the alternative pathway (AP) of complement. After binding of CFB to C3b, activation of the AP depends on the proteolytic cleavage of CFB by factor D to generate the C3 convertase (C3bBb). The C3 convertase contains the ca...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431595/ https://www.ncbi.nlm.nih.gov/pubmed/34502486 http://dx.doi.org/10.3390/ijms22179580 |