Global Trends in Cancer Nanotechnology: A Qualitative Scientific Mapping Using Content-Based and Bibliometric Features for Machine Learning Text Classification

SIMPLE SUMMARY: This study is a new way of providing potential opportunities for prevention, diagnosis, and therapy to investigate the comprehensive trends in cancer nanotechnology research. This paper applied the qualitative method of bibliometric analysis on cancer nanotechnology using the PubMed database during the years 2000–2021. It mined nearly 50,000 papers published in multiple reputed journals. The impact of our findings is significant, which focuses on hybrid medical models and content-based and bibliometric features for machine learning models in cancer detection, diagnosis, imaging, and therapy related to cancer nanotechnology in the world. We mainly identified and classified the top and significant keywords, countries, authors, affiliations, and research areas representing the documents in the top 100 journals in cancer nanotechnology, which will help researchers explore more powerful anticancer nanomedicines in the next five to ten years. ABSTRACT: This study presents a new way to investigate comprehensive trends in cancer nanotechnology research in different countries, institutions, and journals providing critical insights to prevention, diagnosis, and therapy. This paper applied the qualitative method of bibliometric analysis on cancer nanotechnology using the PubMed database during the years 2000–2021. Inspired by hybrid medical models and content-based and bibliometric features for machine learning models, our results show cancer nanotechnology studies have expanded exponentially since 2010. The highest production of articles in cancer nanotechnology is mainly from US institutions, with several countries, notably the USA, China, the UK, India, and Iran as concentrated focal points as centers of cancer nanotechnology research, especially in the last five years. The analysis shows the greatest overlap between nanotechnology and DNA, RNA, iron oxide or mesoporous silica, breast cancer, and cancer diagnosis and cancer treatment. Moreover, more than 50% of the information related to the keywords, authors, institutions, journals, and countries are considerably investigated in the form of publications from the top 100 journals. This study has the potential to provide past and current lines of research that can unmask comprehensive trends in cancer nanotechnology, key research topics, or the most productive countries and authors in the field.