Identification and Phenotypic Characterization of Hsp90 Phosphorylation Sites That Modulate Virulence Traits in the Major Human Fungal Pathogen Candida albicans

The highly conserved, ubiquitous molecular chaperone Hsp90 is a key regulator of cellular proteostasis and environmental stress responses. In human pathogenic fungi, which kill more than 1.6 million patients each year worldwide, Hsp90 governs cellular morphogenesis, drug resistance, and virulence. Y...

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Detalles Bibliográficos
Autores principales: Alaalm, Leenah, Crunden, Julia L., Butcher, Mark, Obst, Ulrike, Whealy, Ryann, Williamson, Carolyn E., O’Brien, Heath E., Schaffitzel, Christiane, Ramage, Gordon, Spencer, James, Diezmann, Stephanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431828/
https://www.ncbi.nlm.nih.gov/pubmed/34513723
http://dx.doi.org/10.3389/fcimb.2021.637836

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