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Uev1A promotes breast cancer cell migration by up-regulating CT45A expression via the AKT pathway

BACKGROUND: UEV1A encodes a ubiquitin-E2 variant closely associated with tumorigenesis and metastasis, but its underlying mechanism in promoting metastasis remains to be investigated. METHODS: In this study, we experimentally manipulated UEV1A and CT45A gene expression and monitored their effects on...

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Detalles Bibliográficos
Autores principales: Niu, Tong, Wu, Zhaojia, Xiao, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431945/
https://www.ncbi.nlm.nih.gov/pubmed/34503444
http://dx.doi.org/10.1186/s12885-021-08750-3