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Uev1A promotes breast cancer cell migration by up-regulating CT45A expression via the AKT pathway
BACKGROUND: UEV1A encodes a ubiquitin-E2 variant closely associated with tumorigenesis and metastasis, but its underlying mechanism in promoting metastasis remains to be investigated. METHODS: In this study, we experimentally manipulated UEV1A and CT45A gene expression and monitored their effects on...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431945/ https://www.ncbi.nlm.nih.gov/pubmed/34503444 http://dx.doi.org/10.1186/s12885-021-08750-3 |