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Efficacy, Toxicity, and Pharmacokinetics of Intra-Arterial Chemotherapy Versus Intravenous Chemotherapy for Retinoblastoma in Animal Models and Patients

PURPOSE: Through controlled comparative rabbit experiments and parallel patient studies, our purpose was to understand mechanisms underlying differences in efficacy and toxicity between intra-arterial chemotherapy (IAC) and intravenous chemotherapy (IVC). METHODS: In rabbits, ocular tissue drug leve...

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Detalles Bibliográficos
Autores principales: Daniels, Anthony B., Froehler, Michael T., Kaczmarek, Jessica V., Bogan, Carley M., Santapuram, Pranav R., Pierce, Janene M., Chen, Sheau-Chiann, Schremp, Emma A., Boyd, Kelli L., Tao, Yuankai K., Calcutt, Marion W., Koyama, Tatsuki, Richmond, Ann, Friedman, Debra L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431978/
https://www.ncbi.nlm.nih.gov/pubmed/34495330
http://dx.doi.org/10.1167/tvst.10.11.10