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Oocyte Vitrification for Fertility Preservation in Women with Benign Gynecologic Disease: French Clinical Practice Guidelines Developed by a Modified Delphi Consensus Process

International guidelines are published to provide standardized information and fertility preservation (FP) care for adults and children. The purpose of the study was to conduct a modified Delphi process for generating FP guidelines for BGD. A steering committee identified 42 potential FP practices f...

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Detalles Bibliográficos
Autores principales: Courbiere, Blandine, Le Roux, Enora, Mathieu d’Argent, Emmanuelle, Torre, Antoine, Patrat, Catherine, Poncelet, Christophe, Montagut, Jacques, Gremeau, Anne-Sophie, Creux, Hélène, Peigné, Maëliss, Chanavaz-Lacheray, Isabella, Dirian, Lara, Fritel, Xavier, Pouly, Jean-Luc, Fauconnier, Arnaud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8432013/
https://www.ncbi.nlm.nih.gov/pubmed/34501257
http://dx.doi.org/10.3390/jcm10173810
Descripción
Sumario:International guidelines are published to provide standardized information and fertility preservation (FP) care for adults and children. The purpose of the study was to conduct a modified Delphi process for generating FP guidelines for BGD. A steering committee identified 42 potential FP practices for BGD. Then 114 key stakeholders were asked to participate in a modified Delphi process via two online survey rounds and a final meeting. Consensus was reached for 28 items. Among them, stakeholders rated age-specific information concerning the risk of diminished ovarian reserve after surgery as important but rejected proposals setting various upper and lower age limits for FP. All women should be informed about the benefit/risk balance of oocyte vitrification—in particular about the likelihood of live birth according to age. FP should not be offered in rASRM stages I and II endometriosis without endometriomas. These guidelines could be useful for gynecologists to identify situations at risk of infertility and to better inform women with BGDs who might need personalized counseling for FP.