Biologic and Therapeutic Implications of Genomic Alterations in Acute Lymphoblastic Leukemia

Acute lymphoblastic leukemia (ALL) is the most successful paradigm of how risk-adapted therapy and detailed understanding of the genetic alterations driving leukemogenesis and therapeutic response may dramatically improve treatment outcomes, with cure rates now exceeding 90% in children. However, AL...

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Detalles Bibliográficos
Autores principales: Iacobucci, Ilaria, Kimura, Shunsuke, Mullighan, Charles G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8432032/
https://www.ncbi.nlm.nih.gov/pubmed/34501239
http://dx.doi.org/10.3390/jcm10173792

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