New Indications for Liver Transplantation

Liver transplantation (LT) is an important therapeutic option for the treatment of several liver diseases. Modern LT is characterized by remarkable improvements in post-transplant patient survival, graft survival, and quality of life. Thanks to these great improvements, indications for LT are expand...

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Autores principales: Zanetto, Alberto, Shalaby, Sarah, Gambato, Martina, Germani, Giacomo, Senzolo, Marco, Bizzaro, Debora, Russo, Francesco Paolo, Burra, Patrizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8432035/
https://www.ncbi.nlm.nih.gov/pubmed/34501314
http://dx.doi.org/10.3390/jcm10173867
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author Zanetto, Alberto
Shalaby, Sarah
Gambato, Martina
Germani, Giacomo
Senzolo, Marco
Bizzaro, Debora
Russo, Francesco Paolo
Burra, Patrizia
author_facet Zanetto, Alberto
Shalaby, Sarah
Gambato, Martina
Germani, Giacomo
Senzolo, Marco
Bizzaro, Debora
Russo, Francesco Paolo
Burra, Patrizia
author_sort Zanetto, Alberto
collection PubMed
description Liver transplantation (LT) is an important therapeutic option for the treatment of several liver diseases. Modern LT is characterized by remarkable improvements in post-transplant patient survival, graft survival, and quality of life. Thanks to these great improvements, indications for LT are expanding. Nowadays, clinical conditions historically considered exclusion criteria for LT, have been considered new indications for LT, showing survival advantages for patients. In this review, we provide an updated overview of the principal newer indications for LT, with particular attention to alcoholic hepatitis, acute-on-chronic liver failure (ACLF), cholangiocarcinoma and colorectal cancer metastases.
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spelling pubmed-84320352021-09-11 New Indications for Liver Transplantation Zanetto, Alberto Shalaby, Sarah Gambato, Martina Germani, Giacomo Senzolo, Marco Bizzaro, Debora Russo, Francesco Paolo Burra, Patrizia J Clin Med Review Liver transplantation (LT) is an important therapeutic option for the treatment of several liver diseases. Modern LT is characterized by remarkable improvements in post-transplant patient survival, graft survival, and quality of life. Thanks to these great improvements, indications for LT are expanding. Nowadays, clinical conditions historically considered exclusion criteria for LT, have been considered new indications for LT, showing survival advantages for patients. In this review, we provide an updated overview of the principal newer indications for LT, with particular attention to alcoholic hepatitis, acute-on-chronic liver failure (ACLF), cholangiocarcinoma and colorectal cancer metastases. MDPI 2021-08-28 /pmc/articles/PMC8432035/ /pubmed/34501314 http://dx.doi.org/10.3390/jcm10173867 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Zanetto, Alberto
Shalaby, Sarah
Gambato, Martina
Germani, Giacomo
Senzolo, Marco
Bizzaro, Debora
Russo, Francesco Paolo
Burra, Patrizia
New Indications for Liver Transplantation
title New Indications for Liver Transplantation
title_full New Indications for Liver Transplantation
title_fullStr New Indications for Liver Transplantation
title_full_unstemmed New Indications for Liver Transplantation
title_short New Indications for Liver Transplantation
title_sort new indications for liver transplantation
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8432035/
https://www.ncbi.nlm.nih.gov/pubmed/34501314
http://dx.doi.org/10.3390/jcm10173867
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