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Poorer Exercise Accommodation of Regional Systolic Myocardial Motion after Spironolactone Treatment in Heart Failure Patients with Preserved Ejection Fraction and Ventricular Dyssynchrony

Patients with heart failure and preserved ejection fraction (HFpEF) are known to have reduced systolic myocardial velocity (Sm) with impaired accommodation to exercise. We tested the impact of an aldosterone antagonist on Sm at rest and post-exercise. Forty-nine HFpEF patients (65 ± 11 years, 24 mal...

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Detalles Bibliográficos
Autores principales: Yu, Chih-Chieh, Chiu, Fu-Chun, Tsai, Chia-Ti, Wang, Yi-Chih, Lai, Ling-Ping, Hwang, Juey-Jen, Lin, Jiunn-Lee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8432135/
https://www.ncbi.nlm.nih.gov/pubmed/34501280
http://dx.doi.org/10.3390/jcm10173827