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Extracellular GABA waves regulate coincidence detection in excitatory circuits

KEY POINTS: Rapid changes in neuronal network activity trigger widespread waves of extracellular GABA in hippocampal neuropil. Elevations of extracellular GABA narrow the coincidence detection window for excitatory inputs to CA1 pyramidal cells. GABA transporters control the effect of extracellular...

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Detalles Bibliográficos
Autores principales: Sylantyev, Sergiy, Savtchenko, Leonid P., O'Neill, Nathanael, Rusakov, Dmitri A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8432164/
https://www.ncbi.nlm.nih.gov/pubmed/32667048
http://dx.doi.org/10.1113/JP279744

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