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The Defect in Regulatory T Cells in Psoriasis and Therapeutic Approaches
Psoriasis is a chronic inflammatory skin disease characterized by accelerated tumor necrosis factor-α/interleukin (IL)-23/IL-17 axis. Patients with psoriasis manifest functional defects in CD4(+)CD25(+) forkhead box protein 3 (Foxp3)(+) regulatory T cells (Tregs), which suppress the excess immune re...
Autores principales: | Kanda, Naoko, Hoashi, Toshihiko, Saeki, Hidehisa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8432197/ https://www.ncbi.nlm.nih.gov/pubmed/34501328 http://dx.doi.org/10.3390/jcm10173880 |
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