The C-terminus of non-structural protein 1 (NS1) in H5N8 clade 2.3.4.4 avian influenza virus affects virus fitness in human cells and virulence in mice

Avian influenza viruses (AIV) H5N8 clade 2.3.4.4 pose a public health threat but the viral factors relevant for its potential adaptation to mammals are largely unknown. The non-structural protein 1 (NS1) of influenza viruses is an essential interferon antagonist. It commonly consists of 230 amino ac...

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Detalles Bibliográficos
Autores principales: Blaurock, Claudia, Blohm, Ulrike, Luttermann, Christine, Holzerland, Julia, Scheibner, David, Schäfer, Alexander, Groseth, Allison, Mettenleiter, Thomas C., Abdelwhab, Elsayed M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8432360/
https://www.ncbi.nlm.nih.gov/pubmed/34420477
http://dx.doi.org/10.1080/22221751.2021.1971568

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