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Performance of scores in the prediction of clinical outcomes in patients admitted from the emergency service

OBJECTIVE: to evaluate the performance of the quickSOFA scores and Systemic Inflammatory Response Syndrome as predictors of clinical outcomes in patients admitted to an emergency service. METHOD: a retrospective cohort study, involving adult clinical patients admitted to the emergency service. Analy...

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Autores principales: da Silva, Luana Matuella Figueira, Diogo, Luciano Passamini, Vieira, Letícia Becker, Michielin, Fabiano Da Costa, Santarem, Michelle Dornelles, Machado, Maria Luiza Paz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Escola de Enfermagem de Ribeirão Preto / Universidade de São Paulo 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8432508/
https://www.ncbi.nlm.nih.gov/pubmed/34495190
http://dx.doi.org/10.1590/1518-8345.4722.3479
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author da Silva, Luana Matuella Figueira
Diogo, Luciano Passamini
Vieira, Letícia Becker
Michielin, Fabiano Da Costa
Santarem, Michelle Dornelles
Machado, Maria Luiza Paz
author_facet da Silva, Luana Matuella Figueira
Diogo, Luciano Passamini
Vieira, Letícia Becker
Michielin, Fabiano Da Costa
Santarem, Michelle Dornelles
Machado, Maria Luiza Paz
author_sort da Silva, Luana Matuella Figueira
collection PubMed
description OBJECTIVE: to evaluate the performance of the quickSOFA scores and Systemic Inflammatory Response Syndrome as predictors of clinical outcomes in patients admitted to an emergency service. METHOD: a retrospective cohort study, involving adult clinical patients admitted to the emergency service. Analysis of the ROC curve was performed to assess the prognostic indexes between scores and outcomes of interest. Multivariate analysis used Poisson regression with robust variance, evaluating the relationship between variables with biological plausibility and outcomes. RESULTS: 122 patients were selected, 58.2% developed sepsis. Of these, 44.3% had quickSOFA ≥2 points, 87% developed sepsis, 55.6% septic shock and 38.9% died. In the evaluation of Systemic Inflammatory Response Syndrome, 78.5% obtained results >2 points; of these, 66.3% developed sepsis, 40% septic shock and 29.5% died. quickSOFA ≥2 showed greater specificity for diagnosis of sepsis in 86% of the cases, for septic shock 70% and for mortality 64%, whereas the second score showed better results for sensitivity with diagnosis of sepsis in 87.5%, septic shock in 92.7% and death in 90.3%. CONCLUSION: quickSOFA showed by its practicality that it can be used clinically within the emergency services, bringing clinical applicability from the risk classification of patients for the early recognition of unfavorable outcomes.
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spelling pubmed-84325082021-09-16 Performance of scores in the prediction of clinical outcomes in patients admitted from the emergency service da Silva, Luana Matuella Figueira Diogo, Luciano Passamini Vieira, Letícia Becker Michielin, Fabiano Da Costa Santarem, Michelle Dornelles Machado, Maria Luiza Paz Rev Lat Am Enfermagem Original Article OBJECTIVE: to evaluate the performance of the quickSOFA scores and Systemic Inflammatory Response Syndrome as predictors of clinical outcomes in patients admitted to an emergency service. METHOD: a retrospective cohort study, involving adult clinical patients admitted to the emergency service. Analysis of the ROC curve was performed to assess the prognostic indexes between scores and outcomes of interest. Multivariate analysis used Poisson regression with robust variance, evaluating the relationship between variables with biological plausibility and outcomes. RESULTS: 122 patients were selected, 58.2% developed sepsis. Of these, 44.3% had quickSOFA ≥2 points, 87% developed sepsis, 55.6% septic shock and 38.9% died. In the evaluation of Systemic Inflammatory Response Syndrome, 78.5% obtained results >2 points; of these, 66.3% developed sepsis, 40% septic shock and 29.5% died. quickSOFA ≥2 showed greater specificity for diagnosis of sepsis in 86% of the cases, for septic shock 70% and for mortality 64%, whereas the second score showed better results for sensitivity with diagnosis of sepsis in 87.5%, septic shock in 92.7% and death in 90.3%. CONCLUSION: quickSOFA showed by its practicality that it can be used clinically within the emergency services, bringing clinical applicability from the risk classification of patients for the early recognition of unfavorable outcomes. Escola de Enfermagem de Ribeirão Preto / Universidade de São Paulo 2021-09-03 /pmc/articles/PMC8432508/ /pubmed/34495190 http://dx.doi.org/10.1590/1518-8345.4722.3479 Text en Copyright © 2021 Revista Latino-Americana de Enfermagem https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
da Silva, Luana Matuella Figueira
Diogo, Luciano Passamini
Vieira, Letícia Becker
Michielin, Fabiano Da Costa
Santarem, Michelle Dornelles
Machado, Maria Luiza Paz
Performance of scores in the prediction of clinical outcomes in patients admitted from the emergency service
title Performance of scores in the prediction of clinical outcomes in patients admitted from the emergency service
title_full Performance of scores in the prediction of clinical outcomes in patients admitted from the emergency service
title_fullStr Performance of scores in the prediction of clinical outcomes in patients admitted from the emergency service
title_full_unstemmed Performance of scores in the prediction of clinical outcomes in patients admitted from the emergency service
title_short Performance of scores in the prediction of clinical outcomes in patients admitted from the emergency service
title_sort performance of scores in the prediction of clinical outcomes in patients admitted from the emergency service
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8432508/
https://www.ncbi.nlm.nih.gov/pubmed/34495190
http://dx.doi.org/10.1590/1518-8345.4722.3479
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