Hemozoin-mediated inflammasome activation limits long-lived anti-malarial immunity

During acute malaria, most individuals mount robust inflammatory responses that limit parasite burden. However, long-lived sterilizing anti-malarial memory responses are not efficiently induced, even following repeated Plasmodium exposures. Using multiple Plasmodium species, genetically modified par...

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Detalles Bibliográficos
Autores principales: Pack, Angela D., Schwartzhoff, Patrick V., Zacharias, Zeb R., Fernandez-Ruiz, Daniel, Heath, William R., Gurung, Prajwal, Legge, Kevin L., Janse, Chris J., Butler, Noah S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8432597/
https://www.ncbi.nlm.nih.gov/pubmed/34433049
http://dx.doi.org/10.1016/j.celrep.2021.109586

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8432597/
https://www.ncbi.nlm.nih.gov/pubmed/34433049
http://dx.doi.org/10.1016/j.celrep.2021.109586

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