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Hemozoin-mediated inflammasome activation limits long-lived anti-malarial immunity
During acute malaria, most individuals mount robust inflammatory responses that limit parasite burden. However, long-lived sterilizing anti-malarial memory responses are not efficiently induced, even following repeated Plasmodium exposures. Using multiple Plasmodium species, genetically modified par...
Autores principales: | Pack, Angela D., Schwartzhoff, Patrick V., Zacharias, Zeb R., Fernandez-Ruiz, Daniel, Heath, William R., Gurung, Prajwal, Legge, Kevin L., Janse, Chris J., Butler, Noah S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8432597/ https://www.ncbi.nlm.nih.gov/pubmed/34433049 http://dx.doi.org/10.1016/j.celrep.2021.109586 |
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