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Saffron extract attenuates neuroinflammation in rmTBI mouse model by suppressing NLRP3 inflammasome activation via SIRT1
Traumatic brain injury (TBI) remains a major cause of morbidity and disability worldwide and a healthcare burden. TBI is an important risk factor for neurodegenerative diseases hallmarked by exacerbated neuroinflammation. Neuroinflammation in the cerebral cortex plays a critical role in secondary in...
Autores principales: | Shaheen, Mariam J., Bekdash, Amira M., Itani, Hana A., Borjac, Jamilah M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8432768/ https://www.ncbi.nlm.nih.gov/pubmed/34506597 http://dx.doi.org/10.1371/journal.pone.0257211 |
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