A variant ECE1 allele contributes to reduced pathogenicity of Candida albicans during vulvovaginal candidiasis

Vulvovaginal candidiasis (VVC), caused primarily by the human fungal pathogen Candida albicans, results in significant quality-of-life issues for women worldwide. Candidalysin, a toxin derived from a polypeptide (Ece1p) encoded by the ECE1 gene, plays a crucial role in driving immunopathology at the...

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Detalles Bibliográficos
Autores principales: Liu, Junyan, Willems, Hubertine M. E., Sansevere, Emily A., Allert, Stefanie, Barker, Katherine S., Lowes, David J., Dixson, Andrew C., Xu, Zhenbo, Miao, Jian, DeJarnette, Christian, Tournu, Helene, Palmer, Glen E., Richardson, Jonathan P., Barrera, Francisco N., Hube, Bernhard, Naglik, Julian R., Peters, Brian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8432879/
https://www.ncbi.nlm.nih.gov/pubmed/34506615
http://dx.doi.org/10.1371/journal.ppat.1009884

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