Inhaled corticosteroids in COPD: Personalising the therapeutic choice

There has been a recent surge in interest in the role of inhaled corticosteroids (ICS) in the treatment of COPD, especially regarding patients with high eosinophil counts. Evidence has shown that despite the increase in localised adverse effects and a small increase in non-fatal pneumonia events wit...

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Detalles Bibliográficos
Autores principales: Shaw, J A, Irusen, E M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: South African Medical Association 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8432921/
https://www.ncbi.nlm.nih.gov/pubmed/34541493
http://dx.doi.org/10.7196/AJTCCM.2018.v24i1.184
Descripción
Sumario:There has been a recent surge in interest in the role of inhaled corticosteroids (ICS) in the treatment of COPD, especially regarding patients with high eosinophil counts. Evidence has shown that despite the increase in localised adverse effects and a small increase in non-fatal pneumonia events with ICS use, ICS still have an important role to play in reducing exacerbation rates and addressing the inflammation that is at the heart of the pathogenesis of COPD. Current international guidelines recommend the use of ICS only in patients with severe disease. This review examines the potential role of ICS in all COPD patients.

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