Kynurenic acid may underlie sex-specific immune responses to COVID-19

Coronavirus disease 2019 (COVID-19) has poorer clinical outcomes in males than in females, and immune responses underlie these sex-related differences. Because immune responses are, in part, regulated by metabolites, we examined the serum metabolomes of COVID-19 patients. In male patients, kynurenic...

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Detalles Bibliográficos
Autores principales: Cai, Yuping, Kim, Daniel J., Takahashi, Takehiro, Broadhurst, David I., Yan, Hong, Ma, Shuangge, Rattray, Nicholas J. W., Casanovas-Massana, Arnau, Israelow, Benjamin, Klein, Jon, Lucas, Carolina, Mao, Tianyang, Moore, Adam J., Muenker, M. Catherine, Oh, Ji Eun, Silva, Julio, Wong, Patrick, Ko, Albert I., Khan, Sajid A., Iwasaki, Akiko, Johnson, Caroline H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Resource
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8432948/
https://www.ncbi.nlm.nih.gov/pubmed/34230210
http://dx.doi.org/10.1126/scisignal.abf8483

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