Plasma from patients with bacterial sepsis or severe COVID-19 induces suppressive myeloid cell production from hematopoietic progenitors in vitro

Bacterial sepsis and severe COVID-19 share similar clinical manifestations and are both associated with dysregulation of the myeloid cell compartment. We previously reported an expanded CD14(+) monocyte state, MS1, in patients with bacterial sepsis and validated expansion of this cell subpopulation...

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Detalles Bibliográficos
Autores principales: Reyes, Miguel, Filbin, Michael R., Bhattacharyya, Roby P., Sonny, Abraham, Mehta, Arnav, Billman, Kianna, Kays, Kyle R., Pinilla-Vera, Mayra, Benson, Maura E., Cosimi, Lisa A., Hung, Deborah T., Levy, Bruce D., Villani, Alexandra-Chloe, Sade-Feldman, Moshe, Baron, Rebecca M., Goldberg, Marcia B., Blainey, Paul C., Hacohen, Nir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8432955/
https://www.ncbi.nlm.nih.gov/pubmed/34103408
http://dx.doi.org/10.1126/scitranslmed.abe9599

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