Mitochondrial cristae-remodeling protein OPA1 in POMC neurons couples Ca(2+) homeostasis with adipose tissue lipolysis

Appropriate cristae remodeling is a determinant of mitochondrial function and bioenergetics and thus represents a crucial process for cellular metabolic adaptations. Here, we show that mitochondrial cristae architecture and expression of the master cristae-remodeling protein OPA1 in proopiomelanocor...

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Autores principales: Gómez-Valadés, Alicia G., Pozo, Macarena, Varela, Luis, Boudjadja, Mehdi Boutagouga, Ramírez, Sara, Chivite, Iñigo, Eyre, Elena, Haddad-Tóvolli, Roberta, Obri, Arnaud, Milà-Guasch, Maria, Altirriba, Jordi, Schneeberger, Marc, Imbernón, Mónica, Garcia-Rendueles, Angela R., Gama-Perez, Pau, Rojo-Ruiz, Jonathan, Rácz, Bence, Alonso, Maria Teresa, Gomis, Ramon, Zorzano, Antonio, D’Agostino, Giuseppe, Alvarez, Clara V., Nogueiras, Rubén, Garcia-Roves, Pablo M., Horvath, Tamas L., Claret, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8432968/
https://www.ncbi.nlm.nih.gov/pubmed/34343501
http://dx.doi.org/10.1016/j.cmet.2021.07.008

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