MicroRNA-regulated transcriptome analysis identifies four major subtypes with prognostic and therapeutic implications in prostate cancer

MicroRNA (miRNA) deregulation plays a critical role in the heterogeneous development of prostate cancer (PCa) by tuning mRNA levels. Herein, we aimed to characterize the molecular features of PCa by clustering the miRNA-regulated transcriptome with non-negative matrix factorization. Using 478 PCa sa...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, Bing-Biao, Lei, Han-Qi, Xiong, Hai-Yun, Fu, Xing, Shi, Fu, Yang, Xiang-Wei, Yang, Ya-Fei, Liao, Guo-Long, Feng, Yu-Peng, Jiang, Dong-Gen, Pang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8433071/
https://www.ncbi.nlm.nih.gov/pubmed/34527198
http://dx.doi.org/10.1016/j.csbj.2021.08.046

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8433071/
https://www.ncbi.nlm.nih.gov/pubmed/34527198
http://dx.doi.org/10.1016/j.csbj.2021.08.046

Ejemplares similares