Genomic characterization and outcome evaluation of kinome fusions in lung cancer revealed novel druggable fusions

Kinase fusions represent an important type of somatic alterations that promote oncogenesis and serve as diagnostic markers in lung cancer. We aimed to identify the landscape of clinically relevant kinase fusions in Chinese lung cancer and to explore rare kinase rearrangements; thus, providing valuab...

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Detalles Bibliográficos
Autores principales: Li, Binghao, Qu, Hao, Zhang, Jing, Pan, Weibo, Liu, Meng, Yan, Xiaobo, Huang, Xin, He, Xuexin, Lin, Dong, Liu, Sisi, Guan, Ruting, Wu, Yong, Ou, Qiuxiang, Bao, Hua, Xu, Youbin, Wu, Xue, Shao, Yang, Lin, Nong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8433182/
https://www.ncbi.nlm.nih.gov/pubmed/34508169
http://dx.doi.org/10.1038/s41698-021-00221-z

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