Cardiomyocyte electrical-mechanical synchronized model for high-content, dose-quantitative and time-dependent drug assessment

Cardiovascular diseases have emerged as a significant threat to human health. However, drug development is a time-consuming and costly process, and few drugs pass the preclinical assessment of safety and efficacy. The existing patch-clamp, Ca(2+) imaging, and microelectrode array technologies in car...

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Detalles Bibliográficos
Autores principales: Fang, Jiaru, Wei, Xinwei, Li, Hongbo, Hu, Ning, Liu, Xingxing, Xu, Dongxin, Zhang, Tao, Wan, Hao, Wang, Ping, Xie, Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8433219/
https://www.ncbi.nlm.nih.gov/pubmed/34567740
http://dx.doi.org/10.1038/s41378-021-00247-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8433219/
https://www.ncbi.nlm.nih.gov/pubmed/34567740
http://dx.doi.org/10.1038/s41378-021-00247-0

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