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Application of 3D MAPs pipeline identifies the morphological sequence chondrocytes undergo and the regulatory role of GDF5 in this process

The activity of epiphyseal growth plates, which drives long bone elongation, depends on extensive changes in chondrocyte size and shape during differentiation. Here, we develop a pipeline called 3D Morphometric Analysis for Phenotypic significance (3D MAPs), which combines light-sheet microscopy, se...

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Detalles Bibliográficos
Autores principales:	Rubin, Sarah, Agrawal, Ankit, Stegmaier, Johannes, Krief, Sharon, Felsenthal, Neta, Svorai, Jonathan, Addadi, Yoseph, Villoutreix, Paul, Stern, Tomer, Zelzer, Elazar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8433335/ https://www.ncbi.nlm.nih.gov/pubmed/34508093 http://dx.doi.org/10.1038/s41467-021-25714-0

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