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Miura-ori structured flexible microneedle array electrode for biosignal recording
Highly reliable signal recording with low electrode-skin impedance makes the microneedle array electrode (MAE) a promising candidate for biosignal sensing. However, when used in long-term health monitoring for some incidental diseases, flexible microneedles with perfectly skin-tight fit substrates l...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8433437/ https://www.ncbi.nlm.nih.gov/pubmed/34567766 http://dx.doi.org/10.1038/s41378-021-00259-w |
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author | Hou, Yue Li, Zhaoyu Wang, Ziyu Yu, Hongyu |
author_facet | Hou, Yue Li, Zhaoyu Wang, Ziyu Yu, Hongyu |
author_sort | Hou, Yue |
collection | PubMed |
description | Highly reliable signal recording with low electrode-skin impedance makes the microneedle array electrode (MAE) a promising candidate for biosignal sensing. However, when used in long-term health monitoring for some incidental diseases, flexible microneedles with perfectly skin-tight fit substrates lead to sweat accumulation inside, which will not only affect the signal output but also trigger some skin allergic reactions. In this paper, a flexible MAE on a Miura-ori structured substrate is proposed and fabricated with two-directional in-plane bendability. The results from the comparison tests show enhanced performance in terms of (1) the device reliability by resisting peeling off of the metal layer from the substrate during the operation and (2) air ventilation, achieved from the air-circulating channels, to remove sweat. Bio-signal recordings of electrocardiography (ECG), as well as electromyography (EMG) of the biceps brachii, in both static and dynamic states, are successfully demonstrated with superior accuracy and long-term stability, demonstrating the great potential in health monitoring applications. |
format | Online Article Text |
id | pubmed-8433437 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-84334372021-09-24 Miura-ori structured flexible microneedle array electrode for biosignal recording Hou, Yue Li, Zhaoyu Wang, Ziyu Yu, Hongyu Microsyst Nanoeng Article Highly reliable signal recording with low electrode-skin impedance makes the microneedle array electrode (MAE) a promising candidate for biosignal sensing. However, when used in long-term health monitoring for some incidental diseases, flexible microneedles with perfectly skin-tight fit substrates lead to sweat accumulation inside, which will not only affect the signal output but also trigger some skin allergic reactions. In this paper, a flexible MAE on a Miura-ori structured substrate is proposed and fabricated with two-directional in-plane bendability. The results from the comparison tests show enhanced performance in terms of (1) the device reliability by resisting peeling off of the metal layer from the substrate during the operation and (2) air ventilation, achieved from the air-circulating channels, to remove sweat. Bio-signal recordings of electrocardiography (ECG), as well as electromyography (EMG) of the biceps brachii, in both static and dynamic states, are successfully demonstrated with superior accuracy and long-term stability, demonstrating the great potential in health monitoring applications. Nature Publishing Group UK 2021-07-21 /pmc/articles/PMC8433437/ /pubmed/34567766 http://dx.doi.org/10.1038/s41378-021-00259-w Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Hou, Yue Li, Zhaoyu Wang, Ziyu Yu, Hongyu Miura-ori structured flexible microneedle array electrode for biosignal recording |
title | Miura-ori structured flexible microneedle array electrode for biosignal recording |
title_full | Miura-ori structured flexible microneedle array electrode for biosignal recording |
title_fullStr | Miura-ori structured flexible microneedle array electrode for biosignal recording |
title_full_unstemmed | Miura-ori structured flexible microneedle array electrode for biosignal recording |
title_short | Miura-ori structured flexible microneedle array electrode for biosignal recording |
title_sort | miura-ori structured flexible microneedle array electrode for biosignal recording |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8433437/ https://www.ncbi.nlm.nih.gov/pubmed/34567766 http://dx.doi.org/10.1038/s41378-021-00259-w |
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