Fast Progression in Amyotrophic Lateral Sclerosis Is Associated With Greater TDP-43 Burden in Spinal Cord

Upper and lower motor neuron pathologies are critical to the autopsy diagnosis of amyotrophic lateral sclerosis (ALS). Further investigation is needed to determine how the relative burden of these pathologies affects the disease course. We performed a blinded, retrospective study of 38 ALS patients,...

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Detalles Bibliográficos
Autores principales: Cathcart, Sahara J, Appel, Stanley H, Peterson, Leif E, Greene, Ericka P, Powell, Suzanne Z, Arumanayagam, Anithachristy S, Rivera, Andreana L, Cykowski, Matthew D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8433592/
https://www.ncbi.nlm.nih.gov/pubmed/34383907
http://dx.doi.org/10.1093/jnen/nlab061

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