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Evaluation of the Saponin Content in Panax vietnamensis Acclimatized to Lam Dong Province by HPLC–UV/CAD

Panax vietnamensis, or Vietnamese ginseng (VG), an endemic Panax species in Vietnam, possesses a unique saponin profile and interesting biological activities. This plant is presently in danger of extinction due to over-exploitation, resulting in many preservation efforts towards the geographical acc...

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Autores principales: Nguyen, Huy Truong, Vu-Huynh, Kim Long, Nguyen, Hien Minh, Le, Huong Thuy, Le, Thi Hong Van, Park, Jeong Hill, Nguyen, Minh Duc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8433671/
https://www.ncbi.nlm.nih.gov/pubmed/34500805
http://dx.doi.org/10.3390/molecules26175373
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author Nguyen, Huy Truong
Vu-Huynh, Kim Long
Nguyen, Hien Minh
Le, Huong Thuy
Le, Thi Hong Van
Park, Jeong Hill
Nguyen, Minh Duc
author_facet Nguyen, Huy Truong
Vu-Huynh, Kim Long
Nguyen, Hien Minh
Le, Huong Thuy
Le, Thi Hong Van
Park, Jeong Hill
Nguyen, Minh Duc
author_sort Nguyen, Huy Truong
collection PubMed
description Panax vietnamensis, or Vietnamese ginseng (VG), an endemic Panax species in Vietnam, possesses a unique saponin profile and interesting biological activities. This plant is presently in danger of extinction due to over-exploitation, resulting in many preservation efforts towards the geographical acclimatization of VG. Yet, no information on the saponin content of the acclimatized VG, an important quality indicator, is available. Here, we analyzed the saponin content in the underground parts of two- to five-year-old VG plants acclimatized to Lam Dong province. Nine characteristic saponins, including notoginsenoside-R1, ginsenoside-Rg1, -Rb1, -Rd, majonoside-R1, -R2 vina-ginsenoside-R2, -R11, and pseudoginsenoside-RT4, were simultaneously determined by HPLC coupled with UV and with a charged aerosol detector (CAD). Analyzing the results illustrated that the detection of characteristic ocotillol-type saponins in VG by CAD presented a superior capacity compared with that of UV, thus implying a preferential choice of CAD for the analysis of VG. The quantitative results indicating the saponin content in the underground parts of VG showed an increasing tendency from two to five years old, with the root and the rhizome exhibiting different saponin accumulation patterns. This is the first study that reveals the preliminary success of VG acclimatization and thereby encourages the continuing efforts to develop this valuable saponin-rich plant.
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spelling pubmed-84336712021-09-12 Evaluation of the Saponin Content in Panax vietnamensis Acclimatized to Lam Dong Province by HPLC–UV/CAD Nguyen, Huy Truong Vu-Huynh, Kim Long Nguyen, Hien Minh Le, Huong Thuy Le, Thi Hong Van Park, Jeong Hill Nguyen, Minh Duc Molecules Article Panax vietnamensis, or Vietnamese ginseng (VG), an endemic Panax species in Vietnam, possesses a unique saponin profile and interesting biological activities. This plant is presently in danger of extinction due to over-exploitation, resulting in many preservation efforts towards the geographical acclimatization of VG. Yet, no information on the saponin content of the acclimatized VG, an important quality indicator, is available. Here, we analyzed the saponin content in the underground parts of two- to five-year-old VG plants acclimatized to Lam Dong province. Nine characteristic saponins, including notoginsenoside-R1, ginsenoside-Rg1, -Rb1, -Rd, majonoside-R1, -R2 vina-ginsenoside-R2, -R11, and pseudoginsenoside-RT4, were simultaneously determined by HPLC coupled with UV and with a charged aerosol detector (CAD). Analyzing the results illustrated that the detection of characteristic ocotillol-type saponins in VG by CAD presented a superior capacity compared with that of UV, thus implying a preferential choice of CAD for the analysis of VG. The quantitative results indicating the saponin content in the underground parts of VG showed an increasing tendency from two to five years old, with the root and the rhizome exhibiting different saponin accumulation patterns. This is the first study that reveals the preliminary success of VG acclimatization and thereby encourages the continuing efforts to develop this valuable saponin-rich plant. MDPI 2021-09-03 /pmc/articles/PMC8433671/ /pubmed/34500805 http://dx.doi.org/10.3390/molecules26175373 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Nguyen, Huy Truong
Vu-Huynh, Kim Long
Nguyen, Hien Minh
Le, Huong Thuy
Le, Thi Hong Van
Park, Jeong Hill
Nguyen, Minh Duc
Evaluation of the Saponin Content in Panax vietnamensis Acclimatized to Lam Dong Province by HPLC–UV/CAD
title Evaluation of the Saponin Content in Panax vietnamensis Acclimatized to Lam Dong Province by HPLC–UV/CAD
title_full Evaluation of the Saponin Content in Panax vietnamensis Acclimatized to Lam Dong Province by HPLC–UV/CAD
title_fullStr Evaluation of the Saponin Content in Panax vietnamensis Acclimatized to Lam Dong Province by HPLC–UV/CAD
title_full_unstemmed Evaluation of the Saponin Content in Panax vietnamensis Acclimatized to Lam Dong Province by HPLC–UV/CAD
title_short Evaluation of the Saponin Content in Panax vietnamensis Acclimatized to Lam Dong Province by HPLC–UV/CAD
title_sort evaluation of the saponin content in panax vietnamensis acclimatized to lam dong province by hplc–uv/cad
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8433671/
https://www.ncbi.nlm.nih.gov/pubmed/34500805
http://dx.doi.org/10.3390/molecules26175373
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