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Positive Charges in the Brace Region Facilitate the Membrane Disruption of MLKL-NTR in Necroptosis

Necroptosis is a type of programmed cell death executed through the plasma membrane disruption by mixed lineage kinase domain-like protein (MLKL). Previous studies have revealed that an N-terminal four-helix bundle domain (NBD) of MLKL is the executioner domain for the membrane permeabilization, whi...

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Detalles Bibliográficos
Autores principales:	Yang, Yaqing, Xie, Encheng, Du, Lingyu, Yang, Yu, Wu, Bin, Sun, Liming, Wang, Shuqing, OuYang, Bo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8433767/ https://www.ncbi.nlm.nih.gov/pubmed/34500630 http://dx.doi.org/10.3390/molecules26175194

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