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Automatic Detection of Colorectal Polyps Using Transfer Learning

SIMPLE SUMMARY: Colorectal cancer represents one of the major health problems due to high incidence and mortality rates. A diversity of treatment options as well as a rising population require novel diagnostic tools. The main goal of the research was to develop a novel complex colorectal cancer deci...

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Autores principales: Dulf, Eva-H., Bledea, Marius, Mocan, Teodora, Mocan, Lucian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8433882/
https://www.ncbi.nlm.nih.gov/pubmed/34502594
http://dx.doi.org/10.3390/s21175704
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author Dulf, Eva-H.
Bledea, Marius
Mocan, Teodora
Mocan, Lucian
author_facet Dulf, Eva-H.
Bledea, Marius
Mocan, Teodora
Mocan, Lucian
author_sort Dulf, Eva-H.
collection PubMed
description SIMPLE SUMMARY: Colorectal cancer represents one of the major health problems due to high incidence and mortality rates. A diversity of treatment options as well as a rising population require novel diagnostic tools. The main goal of the research was to develop a novel complex colorectal cancer decision support system based on artificial intelligence. The developed system can classify eight classes of tissue and can identify the malignant areas. In order to allow the easiest and most intuitive interaction with clinicians, the corresponding application was also built. ABSTRACT: Colorectal cancer is the second leading cause of cancer death and ranks third worldwide in diagnosed malignant pathologies (1.36 million new cases annually). An increase in the diversity of treatment options as well as a rising population require novel diagnostic tools. Current diagnostics involve critical human thinking, but the decisional process loses accuracy due to the increased number of modulatory factors involved. The proposed computer-aided diagnosis system analyses each colonoscopy and provides predictions that will help the clinician to make the right decisions. Artificial intelligence is included in the system both offline and online image processing tools. Aiming to improve the diagnostic process of colon cancer patients, an application was built that allows the easiest and most intuitive interaction between medical staff and the proposed diagnosis system. The developed tool uses two networks. The first, a convolutional neural network, is capable of classifying eight classes of tissue with a sensitivity of 98.13% and an F1 score of 98.14%, while the second network, based on semantic segmentation, can identify the malignant areas with a Jaccard index of 75.18%. The results could have a direct impact on personalised medicine combining clinical knowledge with the computing power of intelligent algorithms.
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spelling pubmed-84338822021-09-12 Automatic Detection of Colorectal Polyps Using Transfer Learning Dulf, Eva-H. Bledea, Marius Mocan, Teodora Mocan, Lucian Sensors (Basel) Article SIMPLE SUMMARY: Colorectal cancer represents one of the major health problems due to high incidence and mortality rates. A diversity of treatment options as well as a rising population require novel diagnostic tools. The main goal of the research was to develop a novel complex colorectal cancer decision support system based on artificial intelligence. The developed system can classify eight classes of tissue and can identify the malignant areas. In order to allow the easiest and most intuitive interaction with clinicians, the corresponding application was also built. ABSTRACT: Colorectal cancer is the second leading cause of cancer death and ranks third worldwide in diagnosed malignant pathologies (1.36 million new cases annually). An increase in the diversity of treatment options as well as a rising population require novel diagnostic tools. Current diagnostics involve critical human thinking, but the decisional process loses accuracy due to the increased number of modulatory factors involved. The proposed computer-aided diagnosis system analyses each colonoscopy and provides predictions that will help the clinician to make the right decisions. Artificial intelligence is included in the system both offline and online image processing tools. Aiming to improve the diagnostic process of colon cancer patients, an application was built that allows the easiest and most intuitive interaction between medical staff and the proposed diagnosis system. The developed tool uses two networks. The first, a convolutional neural network, is capable of classifying eight classes of tissue with a sensitivity of 98.13% and an F1 score of 98.14%, while the second network, based on semantic segmentation, can identify the malignant areas with a Jaccard index of 75.18%. The results could have a direct impact on personalised medicine combining clinical knowledge with the computing power of intelligent algorithms. MDPI 2021-08-24 /pmc/articles/PMC8433882/ /pubmed/34502594 http://dx.doi.org/10.3390/s21175704 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Dulf, Eva-H.
Bledea, Marius
Mocan, Teodora
Mocan, Lucian
Automatic Detection of Colorectal Polyps Using Transfer Learning
title Automatic Detection of Colorectal Polyps Using Transfer Learning
title_full Automatic Detection of Colorectal Polyps Using Transfer Learning
title_fullStr Automatic Detection of Colorectal Polyps Using Transfer Learning
title_full_unstemmed Automatic Detection of Colorectal Polyps Using Transfer Learning
title_short Automatic Detection of Colorectal Polyps Using Transfer Learning
title_sort automatic detection of colorectal polyps using transfer learning
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8433882/
https://www.ncbi.nlm.nih.gov/pubmed/34502594
http://dx.doi.org/10.3390/s21175704
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