Ruthenium Olefin Metathesis Catalysts Featuring N-Heterocyclic Carbene Ligands Tagged with Isonicotinic and 4-(Dimethylamino)benzoic Acid Rests: Evaluation of a Modular Synthetic Strategy

A modular and flexible strategy towards the synthesis of N-heterocyclic carbene (NHC) ligands bearing Brønsted base tags has been proposed and then adopted in the preparation of two tagged NHC ligands bearing rests of isonicotinic and 4-(dimethylamino)benzoic acids. Such tagged NHC ligands represent...

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Autores principales: Czarnocki, Stefan, Monsigny, Louis, Sienkiewicz, Michał, Kajetanowicz, Anna, Grela, Karol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8433898/
https://www.ncbi.nlm.nih.gov/pubmed/34500654
http://dx.doi.org/10.3390/molecules26175220
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author Czarnocki, Stefan
Monsigny, Louis
Sienkiewicz, Michał
Kajetanowicz, Anna
Grela, Karol
author_facet Czarnocki, Stefan
Monsigny, Louis
Sienkiewicz, Michał
Kajetanowicz, Anna
Grela, Karol
author_sort Czarnocki, Stefan
collection PubMed
description A modular and flexible strategy towards the synthesis of N-heterocyclic carbene (NHC) ligands bearing Brønsted base tags has been proposed and then adopted in the preparation of two tagged NHC ligands bearing rests of isonicotinic and 4-(dimethylamino)benzoic acids. Such tagged NHC ligands represent an attractive starting point for the synthesis of olefin metathesis ruthenium catalysts tagged in non-dissociating ligands. The influence of the Brønsted basic tags on the activity of such obtained olefin metathesis catalysts has been studied.
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spelling pubmed-84338982021-09-12 Ruthenium Olefin Metathesis Catalysts Featuring N-Heterocyclic Carbene Ligands Tagged with Isonicotinic and 4-(Dimethylamino)benzoic Acid Rests: Evaluation of a Modular Synthetic Strategy Czarnocki, Stefan Monsigny, Louis Sienkiewicz, Michał Kajetanowicz, Anna Grela, Karol Molecules Article A modular and flexible strategy towards the synthesis of N-heterocyclic carbene (NHC) ligands bearing Brønsted base tags has been proposed and then adopted in the preparation of two tagged NHC ligands bearing rests of isonicotinic and 4-(dimethylamino)benzoic acids. Such tagged NHC ligands represent an attractive starting point for the synthesis of olefin metathesis ruthenium catalysts tagged in non-dissociating ligands. The influence of the Brønsted basic tags on the activity of such obtained olefin metathesis catalysts has been studied. MDPI 2021-08-28 /pmc/articles/PMC8433898/ /pubmed/34500654 http://dx.doi.org/10.3390/molecules26175220 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Czarnocki, Stefan
Monsigny, Louis
Sienkiewicz, Michał
Kajetanowicz, Anna
Grela, Karol
Ruthenium Olefin Metathesis Catalysts Featuring N-Heterocyclic Carbene Ligands Tagged with Isonicotinic and 4-(Dimethylamino)benzoic Acid Rests: Evaluation of a Modular Synthetic Strategy
title Ruthenium Olefin Metathesis Catalysts Featuring N-Heterocyclic Carbene Ligands Tagged with Isonicotinic and 4-(Dimethylamino)benzoic Acid Rests: Evaluation of a Modular Synthetic Strategy
title_full Ruthenium Olefin Metathesis Catalysts Featuring N-Heterocyclic Carbene Ligands Tagged with Isonicotinic and 4-(Dimethylamino)benzoic Acid Rests: Evaluation of a Modular Synthetic Strategy
title_fullStr Ruthenium Olefin Metathesis Catalysts Featuring N-Heterocyclic Carbene Ligands Tagged with Isonicotinic and 4-(Dimethylamino)benzoic Acid Rests: Evaluation of a Modular Synthetic Strategy
title_full_unstemmed Ruthenium Olefin Metathesis Catalysts Featuring N-Heterocyclic Carbene Ligands Tagged with Isonicotinic and 4-(Dimethylamino)benzoic Acid Rests: Evaluation of a Modular Synthetic Strategy
title_short Ruthenium Olefin Metathesis Catalysts Featuring N-Heterocyclic Carbene Ligands Tagged with Isonicotinic and 4-(Dimethylamino)benzoic Acid Rests: Evaluation of a Modular Synthetic Strategy
title_sort ruthenium olefin metathesis catalysts featuring n-heterocyclic carbene ligands tagged with isonicotinic and 4-(dimethylamino)benzoic acid rests: evaluation of a modular synthetic strategy
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8433898/
https://www.ncbi.nlm.nih.gov/pubmed/34500654
http://dx.doi.org/10.3390/molecules26175220
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