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Structural Insights in Mammalian Sialyltransferases and Fucosyltransferases: We Have Come a Long Way, but It Is Still a Long Way Down

Mammalian cell surfaces are modified with complex arrays of glycans that play major roles in health and disease. Abnormal glycosylation is a hallmark of cancer; terminal sialic acid and fucose in particular have high levels in tumor cells, with positive implications for malignancy. Increased sialyla...

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Detalles Bibliográficos
Autores principales: Grewal, Ravneet Kaur, Shaikh, Abdul Rajjak, Gorle, Suresh, Kaur, Manjeet, Videira, Paula Alexendra, Cavallo, Luigi, Chawla, Mohit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8433944/
https://www.ncbi.nlm.nih.gov/pubmed/34500643
http://dx.doi.org/10.3390/molecules26175203