A Novel Synthetic Precursor of Styryl Sulfone Neuroprotective Agents Inhibits Neuroinflammatory Responses and Oxidative Stress Damage through the P38 Signaling Pathway in the Cell and Animal Model of Parkinson’s Disease

A novel class of styryl sulfones were designed and synthesized as CAPE derivatives by our work team, which showed a multi-target neuroprotective effect, including antioxidative and anti-neuroinflammatory properties. However, the underlying mechanisms remain unclear. In the present study, the anti-Pa...

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Detalles Bibliográficos
Autores principales: Guo, Ying, Ma, Zhizhong, Ning, Xianling, Chen, Ying, Tian, Chao, Wang, Xiaowei, Zhang, Zhili, Liu, Junyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8433997/
https://www.ncbi.nlm.nih.gov/pubmed/34500807
http://dx.doi.org/10.3390/molecules26175371

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8433997/
https://www.ncbi.nlm.nih.gov/pubmed/34500807
http://dx.doi.org/10.3390/molecules26175371

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