Cargando…

Synthesis of New Highly Functionalized 1H-Indole-2-carbonitriles via Cross-Coupling Reactions

An approach for the preparation of polysubstituted indole-2-carbonitriles through a cross-coupling reaction of compounds 1-(but-2-ynyl)-1H-indole-2-carbonitriles and 1-benzyl-3-iodo-1H-indole-2-carbonitriles is described. The reactivity of indole derivatives with iodine at position 3 was studied usi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hrizi, Asma, Cailler, Manon, Romdhani-Younes, Moufida, Carcenac, Yvan, Thibonnet, Jérôme
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8434198/ https://www.ncbi.nlm.nih.gov/pubmed/34500719 http://dx.doi.org/10.3390/molecules26175287

Ejemplares similares

1,3-Dimethyl-1H-indole-2-carbonitrile
por: Li, Jiang-Sheng, et al.
Publicado: (2009)

Simple synthesis of pyrrolo[3,2-e]indole-1-carbonitriles
por: Trawczyński, Adam, et al.
Publicado: (2013)

2-Methyl-1-phenyl-1H-indole-3-carbonitrile
por: Yang, Kun, et al.
Publicado: (2011)

3-[(E)-2-Phenylethenyl]-1H-indole-6-carbonitrile
por: Ge, Yu-Hua, et al.
Publicado: (2011)

1-(4-Bromophenyl)-2-methyl-1H-indole-3-carbonitrile
por: Yan, Qiao, et al.
Publicado: (2011)

6-Methoxy-2-methyl-1-phenyl-1H-indole-3-carbonitrile
por: Yan, Qiao, et al.
Publicado: (2011)

1-Methoxy-2-methyl-1H-benzo[f]indole-3-carbonitrile
por: Li, Jiang-Sheng, et al.
Publicado: (2009)

2-Methyl-3-p-tolyl-3H-benzo[e]indole-1-carbonitrile
por: Li, Jiang-Sheng, et al.
Publicado: (2009)

2,3-Dihydro-1H-pyrrolo[1,2-a]indole-9-carbonitrile
por: Madeley, Lee G., et al.
Publicado: (2012)

1-Benzyl-2-(1H-indol-3-yl)-5-oxopyrrolidine-2-carbonitrile
por: Tamazyan, Rafael, et al.
Publicado: (2008)

1-(4-Methoxyphenyl)-2-methyl-1H-indole-3-carbonitrile
por: Yan, Qiao, et al.
Publicado: (2011)

1-(2-Chlorophenyl)-6-fluoro-2-methyl-1H-indole-3-carbonitrile
por: Yang, Kun, et al.
Publicado: (2011)

1-[(1-Methyl-1H-imidazol-5-yl)methyl]-1H-indole-5-carbonitrile
por: de Jager, Josephus Jacobus, et al.
Publicado: (2012)

2-Benzyl-6-chloro-1-(4-methylphenyl)-1H-indole-3-carbonitrile
por: Yan, Qiao, et al.
Publicado: (2011)

6-(1H-Indol-3-yl)-4-phenyl-2,2′-bipyridine-5-carbonitrile
por: Zhu, Weijun, et al.
Publicado: (2009)

Demonstration of Green Solvent Performance on O,S,N-Heterocycles Synthesis: Metal-Free Click Chemistry and Buchwald—Hartwig Coupling
por: Campos, Joana F., et al.
Publicado: (2021)

Indole-3-Carbonitriles as DYRK1A Inhibitors by Fragment-Based Drug Design
por: Meine, Rosanna, et al.
Publicado: (2018)

4-(4-Bromophenyl)-6-(1H-indol-3-yl)-2,2′-bipyridine-5-carbonitrile
por: Ramesh, P., et al.
Publicado: (2009)

(±)-trans-5-Benzoyl-2-(1H-indol-3-yl)-4-phenyl-4,5-dihydrofuran-3-carbonitrile
por: Suresh, J., et al.
Publicado: (2012)

4-(2,4-Dichlorophenyl)-6-(1H-indol-3-yl)-2,2′-bipyridine-5-carbonitrile
por: Ramesh, P., et al.
Publicado: (2009)

One-Pot Multicomponent Synthesis and Cytotoxic Evaluation of Novel 7-Substituted-5-(1H-Indol-3-yl)Tetrazolo[1,5-a] Pyrimidine-6-Carbonitrile
por: Radwan, Mohamed A. A., et al.
Publicado: (2020)

3-Amino-1-phenyl-1H-benzo[f]chromene-2-carbonitrile
por: Akkurt, Mehmet, et al.
Publicado: (2013)

Crystal structure of 2-amino-4-phenyl-4H-benzo[h]chromene-3-carbonitrile
por: Mohamed, Shaaban K., et al.
Publicado: (2015)

4-(2,4-Dichlorophenyl)-2-(1H-indol-3-yl)-6-(2-pyridyl)-1,4-dihydropyridine-4-carbonitrile
por: Ramesh, P., et al.
Publicado: (2008)

Synthesis of (Z)-3-[amino(phenyl)methylidene]-1,3-dihydro-2H-indol-2-ones using an Eschenmoser coupling reaction
por: Marek, Lukáš, et al.
Publicado: (2021)

An Efficient Synthesis of Acenaphtho[1,2-b]indole Derivatives via Domino Reaction
por: Zhang, Guo-Ning, et al.
Publicado: (2018)

Crystal structure of 4-(2-azidophenyl)-5-benzoyl-2-(1H-indol-3-yl)-1H-pyrrole-3-carbonitrile
por: Vimala, G., et al.
Publicado: (2015)

5-Benzoyl-2-(1H-indol-3-yl)-4-(4-methylphenyl)-4,5-dihydrofuran-3-carbonitrile
por: Suresh, J., et al.
Publicado: (2012)

Crystal structure of 2-(4-chlorophenyl)-4-(1H-indol-3-yl)-6-phenylpyridine-3-carbonitrile
por: Vishnupriya, R., et al.
Publicado: (2014)

Copper(ii)-catalyzed synthesis of multisubstituted indoles through sequential Chan–Lam and cross-dehydrogenative coupling reactions
por: Chen, Xin, et al.
Publicado: (2020)

Synthesis of Indole-Coupled KYNA Derivatives via C–N Bond Cleavage of Mannich Bases
por: Lőrinczi, Bálint, et al.
Publicado: (2022)

Design and synthesis of hybrid cyclophanes containing thiophene and indole units via Grignard reaction, Fischer indolization and ring-closing metathesis as key steps
por: Kotha, Sambasivarao, et al.
Publicado: (2015)

(±)-trans-5-Benzoyl-4-(3-bromophenyl)-2-(1H-indol-3-yl)-4,5-dihydrofuran-3-carbonitrile
por: Suresh, J., et al.
Publicado: (2012)

Crystal structure of 4-(1H-indol-3-yl)-2-(4-methoxyphenyl)-6-phenylpyridine-3-carbonitrile
por: Vishnupriya, R., et al.
Publicado: (2014)

Synthesis and Reactions of 3-Halogenated 2-CF(3)-Indoles
por: Muzalevskiy, Vasiliy M., et al.
Publicado: (2022)

11H-Dibenzo[b,e]azepine-6-carbonitrile
por: Fan, Guo-Dong, et al.
Publicado: (2008)

9,9-Dibutyl-9H-fluorene-2-carbonitrile
por: Zhao, Dong-dong, et al.
Publicado: (2012)

9-p-Tolyl-9H-carbazole-3-carbonitrile
por: Ramathilagam, C., et al.
Publicado: (2011)

Quinoxaline-2-carbonitrile
por: Fun, Hoong-Kun, et al.
Publicado: (2009)

Quinoline-2-carbonitrile
por: Loh, Wan-Sin, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_scoumsec485u8td4at5o8t4enh