Conjugated β-Cyclodextrin Enhances the Affinity of Folic Acid towards FRα: Molecular Dynamics Study

Drug targeting is a progressive area of research with folate receptor alpha (FRα) receiving significant attention as a biological marker in cancer drug delivery. The binding affinity of folic acid (FA) to the FRα active site provides a basis for recognition of FRα. In this study, FA was conjugated t...

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Detalles Bibliográficos
Autores principales: Al-Thiabat, Mohammad G., Gazzali, Amirah Mohd, Mohtar, Noratiqah, Murugaiyah, Vikneswaran, Kamarulzaman, Ezatul Ezleen, Yap, Beow Keat, Rahman, Noorsaadah Abd, Othman, Rozana, Wahab, Habibah A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8434473/
https://www.ncbi.nlm.nih.gov/pubmed/34500740
http://dx.doi.org/10.3390/molecules26175304

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8434473/
https://www.ncbi.nlm.nih.gov/pubmed/34500740
http://dx.doi.org/10.3390/molecules26175304

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