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Conjugated β-Cyclodextrin Enhances the Affinity of Folic Acid towards FRα: Molecular Dynamics Study
Drug targeting is a progressive area of research with folate receptor alpha (FRα) receiving significant attention as a biological marker in cancer drug delivery. The binding affinity of folic acid (FA) to the FRα active site provides a basis for recognition of FRα. In this study, FA was conjugated t...
Autores principales: | Al-Thiabat, Mohammad G., Gazzali, Amirah Mohd, Mohtar, Noratiqah, Murugaiyah, Vikneswaran, Kamarulzaman, Ezatul Ezleen, Yap, Beow Keat, Rahman, Noorsaadah Abd, Othman, Rozana, Wahab, Habibah A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8434473/ https://www.ncbi.nlm.nih.gov/pubmed/34500740 http://dx.doi.org/10.3390/molecules26175304 |
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