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A Compact Raster Lensless Microscope Based on a Microdisplay
Lensless microscopy requires the simplest possible configuration, as it uses only a light source, the sample and an image sensor. The smallest practical microscope is demonstrated here. In contrast to standard lensless microscopy, the object is located near the lighting source. Raster optical micros...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8434636/ https://www.ncbi.nlm.nih.gov/pubmed/34502832 http://dx.doi.org/10.3390/s21175941 |
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author | Vilà, Anna Moreno, Sergio Canals, Joan Diéguez, Angel |
author_facet | Vilà, Anna Moreno, Sergio Canals, Joan Diéguez, Angel |
author_sort | Vilà, Anna |
collection | PubMed |
description | Lensless microscopy requires the simplest possible configuration, as it uses only a light source, the sample and an image sensor. The smallest practical microscope is demonstrated here. In contrast to standard lensless microscopy, the object is located near the lighting source. Raster optical microscopy is applied by using a single-pixel detector and a microdisplay. Maximum resolution relies on reduced LED size and the position of the sample respect the microdisplay. Contrarily to other sort of digital lensless holographic microscopes, light backpropagation is not required to reconstruct the images of the sample. In a mm-high microscope, resolutions down to 800 nm have been demonstrated even when measuring with detectors as large as 138 μm × 138 μm, with field of view given by the display size. Dedicated technology would shorten measuring time. |
format | Online Article Text |
id | pubmed-8434636 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-84346362021-09-12 A Compact Raster Lensless Microscope Based on a Microdisplay Vilà, Anna Moreno, Sergio Canals, Joan Diéguez, Angel Sensors (Basel) Article Lensless microscopy requires the simplest possible configuration, as it uses only a light source, the sample and an image sensor. The smallest practical microscope is demonstrated here. In contrast to standard lensless microscopy, the object is located near the lighting source. Raster optical microscopy is applied by using a single-pixel detector and a microdisplay. Maximum resolution relies on reduced LED size and the position of the sample respect the microdisplay. Contrarily to other sort of digital lensless holographic microscopes, light backpropagation is not required to reconstruct the images of the sample. In a mm-high microscope, resolutions down to 800 nm have been demonstrated even when measuring with detectors as large as 138 μm × 138 μm, with field of view given by the display size. Dedicated technology would shorten measuring time. MDPI 2021-09-03 /pmc/articles/PMC8434636/ /pubmed/34502832 http://dx.doi.org/10.3390/s21175941 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Vilà, Anna Moreno, Sergio Canals, Joan Diéguez, Angel A Compact Raster Lensless Microscope Based on a Microdisplay |
title | A Compact Raster Lensless Microscope Based on a Microdisplay |
title_full | A Compact Raster Lensless Microscope Based on a Microdisplay |
title_fullStr | A Compact Raster Lensless Microscope Based on a Microdisplay |
title_full_unstemmed | A Compact Raster Lensless Microscope Based on a Microdisplay |
title_short | A Compact Raster Lensless Microscope Based on a Microdisplay |
title_sort | compact raster lensless microscope based on a microdisplay |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8434636/ https://www.ncbi.nlm.nih.gov/pubmed/34502832 http://dx.doi.org/10.3390/s21175941 |
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