Cargando…

A Compact Raster Lensless Microscope Based on a Microdisplay

Lensless microscopy requires the simplest possible configuration, as it uses only a light source, the sample and an image sensor. The smallest practical microscope is demonstrated here. In contrast to standard lensless microscopy, the object is located near the lighting source. Raster optical micros...

Descripción completa

Detalles Bibliográficos
Autores principales: Vilà, Anna, Moreno, Sergio, Canals, Joan, Diéguez, Angel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8434636/
https://www.ncbi.nlm.nih.gov/pubmed/34502832
http://dx.doi.org/10.3390/s21175941
_version_ 1783751646850842624
author Vilà, Anna
Moreno, Sergio
Canals, Joan
Diéguez, Angel
author_facet Vilà, Anna
Moreno, Sergio
Canals, Joan
Diéguez, Angel
author_sort Vilà, Anna
collection PubMed
description Lensless microscopy requires the simplest possible configuration, as it uses only a light source, the sample and an image sensor. The smallest practical microscope is demonstrated here. In contrast to standard lensless microscopy, the object is located near the lighting source. Raster optical microscopy is applied by using a single-pixel detector and a microdisplay. Maximum resolution relies on reduced LED size and the position of the sample respect the microdisplay. Contrarily to other sort of digital lensless holographic microscopes, light backpropagation is not required to reconstruct the images of the sample. In a mm-high microscope, resolutions down to 800 nm have been demonstrated even when measuring with detectors as large as 138 μm × 138 μm, with field of view given by the display size. Dedicated technology would shorten measuring time.
format Online
Article
Text
id pubmed-8434636
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-84346362021-09-12 A Compact Raster Lensless Microscope Based on a Microdisplay Vilà, Anna Moreno, Sergio Canals, Joan Diéguez, Angel Sensors (Basel) Article Lensless microscopy requires the simplest possible configuration, as it uses only a light source, the sample and an image sensor. The smallest practical microscope is demonstrated here. In contrast to standard lensless microscopy, the object is located near the lighting source. Raster optical microscopy is applied by using a single-pixel detector and a microdisplay. Maximum resolution relies on reduced LED size and the position of the sample respect the microdisplay. Contrarily to other sort of digital lensless holographic microscopes, light backpropagation is not required to reconstruct the images of the sample. In a mm-high microscope, resolutions down to 800 nm have been demonstrated even when measuring with detectors as large as 138 μm × 138 μm, with field of view given by the display size. Dedicated technology would shorten measuring time. MDPI 2021-09-03 /pmc/articles/PMC8434636/ /pubmed/34502832 http://dx.doi.org/10.3390/s21175941 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Vilà, Anna
Moreno, Sergio
Canals, Joan
Diéguez, Angel
A Compact Raster Lensless Microscope Based on a Microdisplay
title A Compact Raster Lensless Microscope Based on a Microdisplay
title_full A Compact Raster Lensless Microscope Based on a Microdisplay
title_fullStr A Compact Raster Lensless Microscope Based on a Microdisplay
title_full_unstemmed A Compact Raster Lensless Microscope Based on a Microdisplay
title_short A Compact Raster Lensless Microscope Based on a Microdisplay
title_sort compact raster lensless microscope based on a microdisplay
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8434636/
https://www.ncbi.nlm.nih.gov/pubmed/34502832
http://dx.doi.org/10.3390/s21175941
work_keys_str_mv AT vilaanna acompactrasterlenslessmicroscopebasedonamicrodisplay
AT morenosergio acompactrasterlenslessmicroscopebasedonamicrodisplay
AT canalsjoan acompactrasterlenslessmicroscopebasedonamicrodisplay
AT dieguezangel acompactrasterlenslessmicroscopebasedonamicrodisplay
AT vilaanna compactrasterlenslessmicroscopebasedonamicrodisplay
AT morenosergio compactrasterlenslessmicroscopebasedonamicrodisplay
AT canalsjoan compactrasterlenslessmicroscopebasedonamicrodisplay
AT dieguezangel compactrasterlenslessmicroscopebasedonamicrodisplay