Inhibition of hyaluronan secretion by novel coumarin compounds and chitin synthesis inhibitors

Elevated plasma levels of hyaluronic acid (HA) is a disease marker in liver pathology and other inflammatory disorders. Inhibition of HA synthesis with coumarin 4-methylumbelliferone (4MU) has a beneficial effect in animal models of fibrosis, inflammation, cancer and metabolic syndrome. 4MU is an ac...

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Detalles Bibliográficos
Autores principales: Tsitrina, Alexandra A, Krasylov, Igor V, Maltsev, Dmitry I, Andreichenko, Irina N, Moskvina, Viktoria S, Ivankov, Dmitry N, Bulgakova, Elena V, Nesterchuk, Mikhail, Shashkovskaya, Vera, Dashenkova, Nataliya O, Khilya, Vladimir P, Mikaelyan, Arsen, Kotelevtsev, Yuri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8434796/
https://www.ncbi.nlm.nih.gov/pubmed/33978736
http://dx.doi.org/10.1093/glycob/cwab038

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